Martin Overseas

• Treatment of Type 2 diabetes mellitus

RYBELSUS® (semaglutide) tablets 3mg, 7 mg or 14 mg is a prescription medicine used along with diet and exercise to improve blood sugar (glucose) in adults with type 2 diabetes.

• It is not known if RYBELSUS® can be used in people who have had pancreatitis
• RYBELSUS® is not for use in people with type 1 diabetes
• It is not known if RYBELSUS® is safe and effective for use in children under 18 years of age

• Key takeaways:

  • Rybelsus (semaglutide) is an oral medication approved to treat Type 2 diabetes. It contains the same active ingredient as Ozempic and Wegovy. Ozempic is approved for Type 2 diabetes, and Wegovy is approved for chronic weight management.

  • Rybelsus is currently being studied for weight loss in clinical trials. These studies involve higher doses than what’s currently approved and available for diabetes. 

  • Results show that an oral semaglutide (Rybelsus) dose of 50 mg results in similar weight loss as Wegovy. Due to these findings, Rybelsus’ manufacturer plans to request FDA approval in 2023. If approved for weight loss, it may be marketed under a different brand name.

Jardiance Met 12.5mg/500mg Tablet should be taken with food at any time of day but you should try to take it at the same time every day. The dose will be decided by your doctor. Don’t stop taking it without asking your doctor. If you do, your blood sugar levels may increase and put you at risk of serious complications like kidney damage and blindness. This medicine is only part of a treatment program that should include a healthy diet, regular exercise, and weight reduction as advised by your doctor.

The most common side effects of this medicine include taste changes, nausea, vomiting, diarrhea, joint pain, urinary tract infection, and yeast infections. Drinking plenty of fluids while using it will help prevent dehydration. Some people may develop fungal infections in the genital area. Maintaining good hygiene can help prevent this.

Before taking this medicine, inform your doctor if you have any kidney or liver problems or a urinary tract infection or if you are on water pills (diuretics). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects. Monitor your blood sugar levels regularly while taking this medicine.

• Treatment of Type 2 diabetes mellitus

XARELTO® is a prescription medicine used to:

• reduce the risk of stroke and blood clots in adults who have a medical condition called atrial fibrillation that is not caused by a heart valve problem. With atrial fibrillation, part of the heart does not beat the way it should. This can lead to the formation of blood clots, which can travel to the brain, causing a stroke, or to other parts of the body
• treat blood clots in the veins of your legs (deep vein thrombosis or DVT) or lungs (pulmonary embolism or PE)
• reduce the risk of blood clots from happening again in adults who continue to be at risk for DVT or PE after receiving treatment for blood clots for at least 6 months
• help prevent a blood clot in the legs and lungs of adults who have just had hip or knee replacement surgery
• help prevent blood clots in certain adults hospitalized for an acute illness and after discharge, who are at risk of getting blood clots because of the loss of or decreased ability to move around (mobility) and other risks for getting blood clots, and who do not have a high risk of bleeding

XARELTO® is used with low dose aspirin to:

• reduce the risk of serious heart problems, heart attack and stroke in adults with coronary artery disease (a condition where the blood supply to the heart is reduced or blocked)
• reduce the risk of a sudden decrease in blood flow to the legs, major amputation, serious heart problems or stroke in adults with peripheral artery disease (a condition where the blood flow to the legs is reduced) and includes adults who have recently had a procedure to improve blood flow to the legs

XARELTO® is used in children to:

• treat blood clots or reduce the risk of blood clots from happening again in children from birth to less than 18 years, after receiving at least 5 days of treatment with injectable or intravenous medicines used to treat blood clots
• help prevent blood clots in children 2 years and older with congenital heart disease after the Fontan procedure

XARELTO® was not studied and is not recommended in children less than 6 months of age who:

• were less than 37 weeks of growth (gestation) at birth
• had less than 10 days of oral feeding, or
• had a body weight of less than 5.7 pounds (2.6 kg)

XARELTO® is a prescription medicine used to:

• reduce the risk of stroke and blood clots in adults who have a medical condition called atrial fibrillation that is not caused by a heart valve problem. With atrial fibrillation, part of the heart does not beat the way it should. This can lead to the formation of blood clots, which can travel to the brain, causing a stroke, or to other parts of the body
• treat blood clots in the veins of your legs (deep vein thrombosis or DVT) or lungs (pulmonary embolism or PE)
• reduce the risk of blood clots from happening again in adults who continue to be at risk for DVT or PE after receiving treatment for blood clots for at least 6 months
• help prevent a blood clot in the legs and lungs of adults who have just had hip or knee replacement surgery
• help prevent blood clots in certain adults hospitalized for an acute illness and after discharge, who are at risk of getting blood clots because of the loss of or decreased ability to move around (mobility) and other risks for getting blood clots, and who do not have a high risk of bleeding

XARELTO® is used with low dose aspirin to:

• reduce the risk of serious heart problems, heart attack and stroke in adults with coronary artery disease (a condition where the blood supply to the heart is reduced or blocked)
• reduce the risk of a sudden decrease in blood flow to the legs, major amputation, serious heart problems or stroke in adults with peripheral artery disease (a condition where the blood flow to the legs is reduced) and includes adults who have recently had a procedure to improve blood flow to the legs

XARELTO® is used in children to:

• treat blood clots or reduce the risk of blood clots from happening again in children from birth to less than 18 years, after receiving at least 5 days of treatment with injectable or intravenous medicines used to treat blood clots
• help prevent blood clots in children 2 years and older with congenital heart disease after the Fontan procedure

XARELTO® was not studied and is not recommended in children less than 6 months of age who:

• were less than 37 weeks of growth (gestation) at birth
• had less than 10 days of oral feeding, or
• had a body weight of less than 5.7 pounds (2.6 kg)

• Treatment of Type 2 diabetes mellitus

Mounjaro 2.5mg KwikPen is a once-weekly injection administered subcutaneously in the abdomen, thigh, or upper arm. It’s essential to rotate injection sites to prevent skin irritation and ensure the proper absorption of the medicine. Take the injection on the same day each week and at the same time, as missing doses or inconsistent use may reduce the effectiveness of the medicine.

Always follow your doctor’s instructions about the dosage, timings, use, and storage of Mounjaro 2.5mg KwikPen. Keep the medicine in a refrigerator (2°C–8°C), but do not freeze it. If left out at room temperature, consult your pharmacist to determine if it is safe to use.

Common side effects of Mounjaro 2.5mg KwikPen are nausea, diarrhea, vomiting, constipation, abdominal pain, and dyspepsia (indigestion). These symptoms are usually mild and tend to improve as your body adjusts to the medicine. However, if these symptoms continue, consult a doctor. Eating smaller meals and staying hydrated can minimize the discomfort from gastrointestinal symptoms.

Mounjaro 2.5mg KwikPen is not suitable for everyone. It must not be used by individuals who have a personal or family history of a rare thyroid cancer (medullary carcinoma) or multiple endocrine neoplasia syndrome type 2 (MEN2). This medicine may increase the risk of these tumors. Pregnant women or those planning to conceive should avoid this medication since animal studies suggest that it may cause potential risks to the unborn baby. Also, talk to your doctor if you are breastfeeding, as the developmental and health benefits of breastfeeding should be kept in mind along with the mother’s clinical needs for Mounjaro 2.5mg KwikPen.

Before starting this medicine, inform your doctor about all the medications you are currently taking to prevent possible interactions. Regularly monitor your blood sugar levels and attend regular check-ups to maintain optimal health. This helps your doctor track your progress, adjust your dosage if needed, and ensure your treatment is safe and effective. Avoid self-medicating, and always consult your doctor if you experience any unusual symptoms.

It is best to take Dytor Plus 10 Tablet in the morning along with food in order to avoid frequent urination at night time. For better results, it is suggested to take it at the same time everyday.  The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.

Dehydration is very common side effect of this medicine. It might lower down the level of calcium, sodium, and magnesium in the blood. Hence, regular monitoring of kidney function and electrolytes is important while using this medicine. It might cause dizziness or tiredness, if happens rise slowly from sitting position or avoid driving.

Before taking this medicine, tell your doctor if you have any liver or kidney disease. Tell your doctor if you are pregnant or breastfeeding. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.

• Treatment of Edema

Heparin is used to prevent blood clots from forming in people who have certain medical conditions or who are undergoing certain medical procedures that increase the chance that clots will form. Heparin is also used to stop the growth of clots that have already formed in the blood vessels, but it cannot be used to decrease the size of clots that have already formed. Heparin is also used in small amounts to prevent blood clots from forming in catheters (small plastic tubes through which medication can be administered or blood drawn) that are left in veins over a period of time. Heparin is in a class of medications called anticoagulants ('blood thinners'). It works by decreasing the clotting ability of the blood.Heparin comes as a solution (liquid) to be injected intravenously (into a vein) or deeply under the skin and as a dilute (less concentrated) solution to be injected into intravenous catheters. Heparin should not be injected into a muscle. Heparin is sometimes injected one to six times a day and sometimes given as a slow, continuous injection into the vein. When heparin is used to prevent blood clots from forming in intravenous catheters, it is usually used when the catheter is first put in place, and every time that blood is drawn out of the catheter or medication is given through the catheter.

Heparin may be given to you by a nurse or other healthcare provider, or you may be told to inject the medication by yourself at home. If you will be injecting heparin yourself, a healthcare provider will show you how to inject the medication. Ask your doctor, nurse, or pharmacist if you do not understand these directions or have any questions about where on your body you should inject heparin, how to give the injection, or how to dispose of used needles and syringes after you inject the medication.

If you will be injecting heparin yourself, follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use heparin exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Heparin solution comes in different strengths, and using the wrong strength may cause serious problems. Before giving an injection of heparin, check the package label to make sure it is the strength of heparin solution that your doctor prescribed for you. If the strength of heparin is not correct do not use the heparin and call your doctor or pharmacist right away.

Your doctor may increase or decrease your dose during your heparin treatment. If you will be injecting heparin yourself, be sure you know how much medication you should use.