COVID-19 MEDICINES

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Although vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19), have been developed and distributed, major challenges remain regarding vaccine production and allocation.1 The identification of inexpensive, widely available, and effective therapies against Covid-19 is of great importance. The repurposing of existing medicines that are widely available and that have reasonably well understood safety profiles has appeal.2
One drug that has received considerable public use and interest is ivermectin, which is typically used as an antiparasitic drug. Ivermectin inhibits the chloride channels of helminthic parasites and has been shown to have clinical efficacy for the treatment of onchocerciasis, strongyloidiasis, and ectoparasitic infection (e.g., scabies).3 The in vitro antiviral activity of ivermectin has been explored against a spectrum of viruses, including severe acute respiratory syndrome coronavirus 1, human immunodeficiency virus, dengue virus, Zika virus, yellow fever virus, West Nile virus, Hendra virus, chikungunya virus, Semliki Forest virus, Sindbis virus, and avian influenza virus.4
More than 60 randomized trials of ivermectin for the treatment of Covid-19 have been registered, and findings have been reported for as many as 31 clinical trials.5 The results have been discordant, and various review groups interpret the evidence differently — some advocating for benefits of ivermectin, and others reticent to conclude a benefit.6-8 However, most trials have been small, and several have been withdrawn from publication owing to concerns about credibility.9
To evaluate the efficacy of ivermectin for the prevention of progression of Covid-19 resulting in hospitalization among outpatients with SARS-CoV-2 infection, we conducted a randomized, placebo-controlled, adaptive platform trial (TOGETHER) in the state of Minas Gerais, Brazil. Although various interventions were assessed in this trial, we report here on the use of ivermectin at a dose of 400 μg per kilogram of body weight for 3 days as compared with placebo.

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Although vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19), have been developed and distributed, major challenges remain regarding vaccine production and allocation.1 The identification of inexpensive, widely available, and effective therapies against Covid-19 is of great importance. The repurposing of existing medicines that are widely available and that have reasonably well understood safety profiles has appeal.2

One drug that has received considerable public use and interest is ivermectin, which is typically used as an antiparasitic drug. Ivermectin inhibits the chloride channels of helminthic parasites and has been shown to have clinical efficacy for the treatment of onchocerciasis, strongyloidiasis, and ectoparasitic infection (e.g., scabies).3 The in vitro antiviral activity of ivermectin has been explored against a spectrum of viruses, including severe acute respiratory syndrome coronavirus 1, human immunodeficiency virus, dengue virus, Zika virus, yellow fever virus, West Nile virus, Hendra virus, chikungunya virus, Semliki Forest virus, Sindbis virus, and avian influenza virus.4

More than 60 randomized trials of ivermectin for the treatment of Covid-19 have been registered, and findings have been reported for as many as 31 clinical trials.5 The results have been discordant, and various review groups interpret the evidence differently — some advocating for benefits of ivermectin, and others reticent to conclude a benefit.6-8 However, most trials have been small, and several have been withdrawn from publication owing to concerns about credibility.9

To evaluate the efficacy of ivermectin for the prevention of progression of Covid-19 resulting in hospitalization among outpatients with SARS-CoV-2 infection, we conducted a randomized, placebo-controlled, adaptive platform trial (TOGETHER) in the state of Minas Gerais, Brazil. Although various interventions were assessed in this trial, we report here on the use of ivermectin at a dose of 400 μg per kilogram of body weight for 3 days as compared with placebo.

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Ivermectin (Stromectol) is a medication used for infections caused by certain parasitic worms found in rural tropical areas. Depending on the type of worm being treated, serious side effects can occur. It hasn't been shown to work well for other types of infections.

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Martin Overseas engaged in Offering Pharmaceutical Medicines in wide segment like anti diabetic Asthama anti cancer Anti HIV Dermal Pain Killer Weight management medicines with supply of Quality Products to our Clients our Range of Products are really appreciated by our client

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Martin Overseas engaged in Offering Pharmaceutical Medicines in wide segment like anti diabetic Asthama anti cancer Anti HIV Dermal Pain Killer Weight management medicines with supply of Quality Products to our Clients our Range of Products are really appreciated by our client

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Remdesivir, sold under the brand name Veklury,^[13][14] is a broad-spectrum antiviral medication developed by the biopharmaceutical company Gilead Sciences.^[15] It is administered via injection into a vein.^[16][17] During the COVID‑19 pandemic, remdesivir was approved or authorized for emergency use to treat COVID‑19 in numerous countries.^[18]

Remdesivir was originally developed to treat hepatitis C,^[19] and was subsequently investigated for Ebola virus disease and Marburg virus infections^[20] before being studied as a post-infection treatment for COVID‑19.^[21]

Remdesivir is a prodrug that is intended to allow intracellular delivery of GS-441524 monophosphate and subsequent biotransformation into GS-441524 triphosphate, a ribonucleotide analogue inhibitor of viral RNA polymerase.^[22]

The most common side effect in healthy volunteers is raised blood levels of liver enzymes.^[13] The most common side effect in people with COVID‑19 is nausea.^[13] Side effects may include liver inflammation and an infusion-related reaction with nausea, low blood pressure, and sweating.^[23]

The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication.^[24

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Fabiflu 400 Tablet is an antiviral medicine. It is used for the treatment of mild to moderate coronavirus disease (COVID-19) in adults. It stops the virus from multiplying and therefore, decreases the viral load in the body.

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We are engaged in Offering wide range of Quality Products to our Clients, our Range of Products are really appreciated by our client.

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We are engaged in Offering wide range of Quality Products to our Clients, our Range of Products are really appreciated by our client.

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Martin Overseas engaged in Offering Pharmaceutical Medicines in wide segment like anti diabetic Asthama anti cancer Anti HIV Dermal Pain Killer Weight management medicines with supply of Quality Products to our Clients our Range of Products are really appreciated by our client

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Artesunate is used in the treatment of malaria. It is not used to prevent malaria or to treat severe malaria (where it has affected the brain, lungs or kidneys). Artesunate is an antiparasitic medication. It works by producing harmful chemicals (free radicals) within the malarial parasite, thereby killing it.

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CINKONA 300MG TABLET contains Quinine which belongs to the group of medicines called Antimalarials. It is used to treat malaria